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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e1eb683318a4ab54dd6ed60c51842debd5f4c68c60cb55ef2f9979d8f9d1185' 
  AND token = 'Mk/FAJq9+e3FFWkjmGMVO93WQvCjc99N6D9jqfXBYPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}