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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5c69ff22e39b2556c4c68ba91fcb008c4b4a538f29569a013fc7e9a9549856f' 
  AND token = 'sCGqCplnbq6wWkJGsDHxBsiwYOD0zyBRtW4WRoATDVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}