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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c772064137e1eeb0fd8a40b7c8df49180d60a22c0b1b3628513b0a3cc57f9f09' 
  AND token = 'MHnJWOHEJGezfHhtdh06C3DWySfCsGJ1XOo2neBUWkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}