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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a9c20c0e488cd268bf00e59f9d6ae348c8ffaf29e903aec78f03f22e9fbf33' 
  AND token = '3S91FWrCpr+QlrbTKvbOCwubPkRW8gvr9KSbwPyrDKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}