SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0924a98263f6be0f5d1a1f86182948a216b9ff59ae47daca5f4e6962dcc99e' 
  AND token = 'vIHpzShDxyj6SNfpGRWerb1iOwExuxz5Bh4zcmnD3Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}