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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354de3ae7e4b43788dd515725d8df3db32f6b72d74dd15d7793e5c714455e348' 
  AND token = 'PvmrU2umaQ6a9R+xrAiR6RNWQlTQvHO23M23V55ch0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}