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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d81a2af362a917fa82b8cef3c0b7c8891b0641035e8f9a07d45d9b6e0e588f1' 
  AND token = '8NOmjUiuoKF2pEtAyNzrHzxNjaLpV6IXydfQt8XgaP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}