SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91c20f17f825ebeb1ce086485760cf65dbec1f13a4580db5b93480a12d88408d' 
  AND token = 'JRH8uLOBm11EUewvCKbV7Pvc8UiwWdCM2ZcjsJvCrcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}