SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe8182caa3568f3fa1dd7f07280257e472d681fb7edbd46790d80329a8474c80' 
  AND token = 'Vbdm8+wbNPfgLD5eATwWWIjZO7k3B2EpDh1/xVj+4ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}