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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd528a41162c988ea5708c08c7f48b7ab3cf5007a5cab7931a3aae4259cf3b012' 
  AND token = 'Enun0XEeK3sOmDXpyhMQPHu3rVZehMXx5uHipmbhdwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}