SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0848c94ff0691061df3656e380a1b3a1f4dfe670cebe7f29da2bc5cc4a65b80b' 
  AND token = 'aQCCeXVYVqYLVV1kjHQgwwKk0DyT1QOblymKBnJ8y0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}