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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c155503cb6788eafc6eacb017605b662d5b7ee35a9d526e40771e1867d5a30d' 
  AND token = 'ZMT3AZU1Zy+2MUZGt81MNRFbQUciTGtU0AOK0YXp/ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}