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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d43c0b16d258c4ed72dde3c357e0b7509f23157d1a9507a8108ee36d75591d7' 
  AND token = 'cyHTO6nTKPpcoDKVB4k9EZAqlLm7/lPV+S1fJrH+MEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}