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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea3cc47257da1e57178121f814b88ff32a3e2d99ed990e6a51ad126c3801fb2' 
  AND token = '0duQqucdGUdPffWbdMieVRenOWzPnfJ/HI9IuDbBeZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}