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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '115d7a20104dcb455241a4b4cde7b08f5afd3c06d33e3a6a22b1c79310a43411' 
  AND token = 'hwFMsACf42GAyvB00FqC6fYlnR2nKWyrjO9ExxmbqlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}