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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59fbff0340603101378c38d99d241b6648cdf266d911eff8e425a6ead77f0cd6' 
  AND token = 'WmSb334j2CqjkFYij/W6aFBxdK125tfX0Y0YRzpWCgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}