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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05d01a1695eded8bfc817ca54f8fedcf266b0fa09882d2713fe4ec761d2fff78' 
  AND token = 'tAfRIWTzXRrheFuz7KIM6WsfU6/Rc4Z30pcu2F8Iz34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}