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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ca9fc72e64107774113b71f36cf4d4bb4cc710df309a1af851921368894d21' 
  AND token = 'ofjnnXLbguDGygxDA6mK0GbAEfL+DxQ2ChXheTLzxKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}