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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51ad0bfe8c93a6975b6320b62d1992e6d18fbd5fea5ea62476fcc3cf83f82735' 
  AND token = 'UPSzpr4egyqqEudSBoLr2s23gdKGd2ltGAcFQJKt2No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}