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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d99b2121f95da21e1ee010d8471368a7b7d332f79c417240688047206b45cb2' 
  AND token = '78x+Dc8vOsfvSXWM08P4O0HS0ExEBxYOeiK9Qft598I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}