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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d3fdf35b5d979dc56ce011e18cd748c2c97009102940f6d090d69cc132b1a7' 
  AND token = 'oAK6bhDxxpF8HSVQFX/d3F8F1aFVTA63w+MzeHIV3ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}