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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f7e7d7f893de0814f980dca7a0b4b4a1c0a4e9517cb5dfc692d28e8e181071' 
  AND token = 'sZM5VxZWpf3QL0vdFTgxIUOVV24V7F9uzvzWx+Dhs0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}