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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3129186d672514488ad80521c88bd53a54e5c212e14359aac1f5a7c06c9546ef' 
  AND token = 'c2+5LrY5Q0QhfMCvEB9rMs54vOvxnKA1Zv9AOzg8DJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}