SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edb28ad0d6303bf8243271c1b5e5c64dde2b35d8b802f3b8aaa545eb244bc350' 
  AND token = 'J3Wvt8zk18p0IlXYQxzxm2m/XzyRu42kx9ZSzd/o7t0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}