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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2911eb174f2adee13ac2fbfc8100b1b27b7a9c9f197bb88d77004ff3d964113d' 
  AND token = 'NC0T/gB8ZYzx3p2I7KKVp0O+dyNYrgdhXlPHhG+ccGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}