SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77ca9463cfb4dafb8d4a85c5574e39d7269ce4b800e6d64e30c20edfa674e478' 
  AND token = 'CuHgQIATghvOg8Ylbr/tBULHJaDAQtmmOTiQoHUwlSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}