SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c60276d2584f0dcce67213147a3b9a24fd20c5356be79c37664d1d75f25e6520' 
  AND token = 'KN9cfrrC/Lf6TSM5A4qC6uBXvADPDnXETkR5I2mI5Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}