SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac0fe690fa8da1dfa7ff2249d55be95b787e81383073694d35b395f604a35795' 
  AND token = '69MqPnnPEkdCok8c6kOitn0aQA327uYUHkQu9gO6U9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}