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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48230f0ee2583c6ba0fda3222bfa92555c8fce10ee8565642092e40741644215' 
  AND token = 'EypKyYKta4zrFczitfEF7knG+Z7BhfrgFM5Takz4Ov0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}