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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb2390958726e9c063f03bc624d11ef8d6c1409ff76ffa49e7d28fb797da2ed' 
  AND token = 'E+dfPehFW1f+xW11vbMBrA9B8mOwoEAoQ4XdB3Hc7Go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}