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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de16c9f3b6603dc153cf528536ba05e0b41a3230c9a8af9a2e86deee3a07d9e' 
  AND token = 'H0NfdpZOtEcVYmxZnxjSLNOgr/P4DIt4Ik6vBU+7TOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}