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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a60bb07d5e208c8f03527c32465309b84b70237b5304a0ca5bb816e85b9e50a' 
  AND token = 'xvt5AOchyZsGfNODP64dpZx3UCBeK0rXmkt5yCD2O8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}