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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e43ff02400ee3a7fcb95860251796e19e1f7d07628f7f4e16b4b0c901ea77b5' 
  AND token = 'Fv7Dsnvfqdvvc88gYEDqS9zk8NrgdfxoYlekAkP1Mj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}