SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '147e7efefb1b6d49cb294ea6736765e8e9259c13b19d8c6254a5cc1799220bbd' 
  AND token = 'YyKRnl+PrHLoP8L1h3Vm6uRCbWIkcWz2SEtLz0/pHis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}