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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f72dcb7ed84d12808c26144a558cad2b0167a3160ee51ce13d0cdbc3b12c9044' 
  AND token = 'T3mBgnKU+ndcdi+EkWLVXSR4trP1ZQw8caIEBU5fb/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}