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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1546a5ab5a6855c8fba441f894f46b06e7323b1be645f439dc861bd49f02b9ae' 
  AND token = '+ilGsrqPYZF8rV8ludEiPdVNrjNYB31bfHvgJMO69I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}