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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '611f09ca54580cedbee7427d7bfb7ffcf70f1f83d3b0d399e7b13de3b13d3323' 
  AND token = '1Nxjp6z5eW+a3ksOhRtmnbJfOVm37UH+s7x7LCqeHM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}