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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e297d6f24aed455942e1e26682c5bd9f1c76c930b7425087e4260525fe070f1f' 
  AND token = 'kIRTj9Kucu1wqHXThnKT4L97F2HjaaXAowAANvhiM2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}