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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed58efe566676b652028da935430a4fb079632d4e0553a3aac629ad946a8cc36' 
  AND token = '/2rvVbCNYB/SbMeuClduyQ/G8ZMfHgK3zYMzr2jm3ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}