SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06cf2538794dd877e42d97603a6c197f65a5283da2c45553fa43e082d8f49ebe' 
  AND token = '66nhvW6TU+ebD53eQCEPUc47bMuOWscKWbTMnG2fCew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}