SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf8c6941df496cb9122b34c1de3220590d657780b26e8da0ce70c7002a170d4' 
  AND token = 'lohey9QK0OvGuW97C9hvdN3dtEmIUpP1WBGeWobi8iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}