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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9258a2fc1361273cf8a1804aa49c0c9cb3c3a9e630e144462cb45752dd3fc658' 
  AND token = 'fXB9NwaMBNUTfZIVkla14EbKmmh6VgMVJQo/qtRhcEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}