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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd548d1d608b6b6702d50183a36abc252f40b94477f1cd1766e8bc50517e87b4' 
  AND token = 'iG24WiTyXTfugr5f4SzNM2sqq2/LJyocYxwynkVfhck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}