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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4789f8fba122a9598995d4d617807983f6b2b9f358a6a5b9ea474e1dde7ef650' 
  AND token = 'X5L/iFEVbwrmo/ll9HqbmDwvkHeWs03fyZET3qQ+Yik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}