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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcca365dd3a6f78e20a7666d3f7f031e22d6610603462233a54d483ee4b38991' 
  AND token = 'cqfvBK5jl/CzyY6cVvXG64cHZSLC0aKeb4DfFPKkAog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}