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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b47be6c3dbe53fa79ed4b62450fb8610d2c00231e01a7a454bb0c8afee88a8' 
  AND token = 'BkQgoIuLB9souFY0TQzd/wD6uhyzy8lY1B9Rw5v4lL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}