SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '468878369111ba9cbc3d81c602f30b1614d1c7d7315d96988d90c13ef2fbaed7' 
  AND token = 'W5ISyXICA9uNoEak4h/qnVpACjwD+LjqzWD60gLZeY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}