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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e09b961c1103a3f468909aa220cfa7332c6f3c7e6d636642ecd8b84e8ed344' 
  AND token = 'QgUDB7vbCdVzPYzeF7I+TomffOipAj9MFSc/QkSgd1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}