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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdf322578ff48bf762c667604905b1f0d65f726446aaecb0e3431226cce92bef' 
  AND token = 'yAsB7Mb296LIp8f5BAQ7a2cNtXbb7DKATtvv0nq9zSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}