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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f80af606fdc846c21dedbf67985f89d349227ad7e2213e008bd5ad29294185e' 
  AND token = 'OvVqqNlqWHZ3Or2W6jDhyLKse/dPs14veX9h/3mrpeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}